VivoSight Dx – System Overview

VivoSight Dx is indicated for use in the two-dimensional, cross-sectional, real-time imaging of external tissues of the human body.

 

Breakthrough structural and vascular imaging through multi-beam OCT

The VivoSight Dx handheld probe captures a 6 mm x 6 mm scan and produces an image that visualizes 1 mm deep into the dermis. 

It takes only 15 seconds for a structural scan, and 30 seconds for a dynamic scan which produces both structural and vascular images.

VivoSight images are displayed on a large monitor for review and can be exported for incorporation into patient records.

Image stacks can also be exported to software packages such as VivoTools for further analysis.

Benefits in Clinical Practice

Quickly see below the surface to better inform treatment decisions

  • Helps to find and assess skin pathology
  • Aids in determination of lesion depth and margins for better targeting
  • Measure vessels to aid selection of laser treatment settings
  • Aids in monitoring treatment response
  • Effective communication tool with patients
  • Enhance patient care through better information
Fast, non-invasive scanning without gel

Benefits in Skin Research

Accelerate development timelines and reduce costs

  • Clinic and bench-top versatility
  • Non-invasive scanning of in-vivo and ex-vivo targets
  • VivoTools image analysis software
  • Multiple objective skin and vascular measurements
  • Automated report generation
  • Batch data processing
Easy to operate user interface

How it works 

An optical analogue to ultrasound imaging using lasers

OCT is an imaging technology based on light and optics. Similar to the way ultrasound uses sound waves, VivoSight OCT uses eye-safe infrared scanning laser light to obtain a 3D block of image data at a higher resolution (< 10 μm) compared to other modalities.

With an ultra-wide field of view of 6 mm x 6 mm and a depth of 1 mm, the user is able not only to see deep into the dermis but also get the full picture of the sub-surface microstructure.

OCT filters out directly reflected light (blue) from scattered light (red, dashed) forming an image
The scanning laser beam produces up to 500 cross-sectional slices (frames) per scan, creating a 3D image block that can be reviewed by frame and at any depth
Individual sectional slices put together into a 3D image block ("loaf of bread")

Patented Multi-Beam Technology

The outstanding imaging performance is the result of multi-beam technology. Four beams of light, each focusing at a different depth, give the user not only a higher resolution but also a deeper penetration depth compared to a single beam system.

VivoSight multi-beam technology offers resolution of 7.5 μm throughout the depth of the image
Single beam OCT systems are only able to produce resolution down to 15 μm

What can we see?

Uncovering morphologic and angiographic patterns

Structural OCT

Within 15 seconds, VivoSight Dx performs a structural 6 mm x 6 mm scan and up to 1.0 mm deep.

Simultaneous views, cross sectional “Frame” and “En-face” (bird’s eye) directions, aid in the assessment of the skin condition.

Powerful image processing provides numerical and graphical data output for objective analysis.

Single "Frame" from 6 mm x 6 mm structural scan
En-face view of adnexal structures (hairs, pores, ducts)
Frame view of BCC lesions
Normal fingernail.
Nail with onychomycosis

Dynamic OCT

Within 30 seconds, VivoSight Dx’s sophisticated technology can also detect miniscule motion, which corresponds to blood flow and identifies vascular patterns. Vessel diameter, depth and density can be measured.

Frame view: vascular lesion before and after laser treatment

  Superficial vascular plexus in 3D representation

Evaluation of therapy response: dynamic OCT image, en-face view, of normal skin located on the cheek before and 60 minutes after application of topical brimonidine

VivoSight Screen and User Interface:

View the entire 3D image stack on a single screen VivoSight automatically calculates the characteristics of the Superficial Vascular Plexus.

Plexus depth, modal vessel diameter and vessel density at this level are reported onscreen

 

What can we measure?

VivoSight Dx and VivoTools give you the power to measure the effect of your treatments

VivoSight System Measurements

VivoSight provides a new way to go beyond just clinical photography and subjective evaluation:

Vascular Plexus Profile

Depth of the superficial plexus, modal vessel diameter, and density of vessels at this level.

Epidermal Thickness

Use depth gauge on any frame to determine epidermal thickness.

Adnexal Structure Metrics

En-Face images visualize hairs and pores at the skin surface for counting and measurement.

En-face view of adnexal structures (hairs, pores, ducts)

Extent of Skin Pathology

Assess (suspicious) skin morphology. Measure location and size.

Top image is of normal tissue, bottom image is of scar tissue. Scar depth can easily be measured with onscreen tools

Microneedle Geometric Parameters

Depth of microneedle penetration and pore size. Amount of needle dissolution and swelling over time.

VivoTools Analysis Software Measurements

With the optional VivoTools advanced skin analysis software, additional parameters can be measured for a host of objective, relevant data to describe skin conditions and therapy results:

Surface Roughness

Roughness measures include peak to trough, average roughness and 3D image.

Changes in Vascular Density

Quantify the density of vessels by depth in the dermis.

Average Epidermal Thickness

VivoTools can measure the average epidermal thickness over the entire 6 x 6 mm scan area.

Beam Attenuation

Proxy measure for collagen content.

Specifications

VivoSight Dx is a class-1 laser device, safe for use in an office environment without need for safety glasses

The entire scanning procedure takes typically one minute or less (per examination site) and can be performed by an assistant, so that data can be scientifically analyzed at a later date, if required.

VivoSight Dx OCT laser scanning handpiece