Skin Care Products & Skin Health

Describe skin texture with objective, relevant metrics

VivoSight Dx is indispensable for development of skin care products and for research on general skin health:

  • Quantify the effect of skin care products
  • Objectively compare topicals and anti-aging creams
  • Detect and quantify inflammatory response to skin preparations
  • Determine trend effects at any point in time
  • Analyze skin variation and treatment response as function of demographics and
  • environmental factors
VivoSight Dx skin roughness measurement illustration

In real-time and non-invasively, VivoSight Dx provides objective data on:

  • Skin surface roughness to quantify changes in wrinkles and texture
  • Epidermal thickness and visualization of DEJ 
  • Skin and pores morphology
  • Attenuation coefficient as proxy for collagen density
  • Inflammatory response via vascular changes

Examples:

Measurement of skin roughness parameters

  • Arithmetic mean roughness (Ra)
  • Highest peak to lowest trough (Rz)

Lower to higher Ra values with increased skin roughness. The average surface variations indicated by green (low) and red colors (high)

Visualization of skin recovery

  • Left: Skin surface right after Microneedle Array Patch removed
  • Right: 21 hours later

References:

1. Sarosh Irani, Zahra Turani, Audrey Fotouhi, Steven Daveluy, Darius Mehregan, Wei Chen, Juri Gelovani, Mohammadreza Nasiriavanaki, “The use of optical coherence tomography to analyze the efficacy of skin care products,” Proc. SPIE 10467, Photonics in Dermatology and Plastic Surgery 2018, 1046715 (21 February 2018); doi: 10.1117/12.2291404

2. O’Leary S, Fotouhi A, Turk D, et al. OCT image atlas of healthy skin on sun-exposed areas. Skin Res Technol. 2018;00:1– 17. https://doi.org/10.1111/ srt.12468

3. Braunmuehl T von et. al. Effects of Short-Term Moisturizer Application in Different Ethnic Skin Types: Noninvasive Assessment with Optical Coherence Tomography and Reflectance Confocal Microscopy. Skin Pharmacol Physiol 2018;31:125–133

4. Kislevitz M, Akgul Y, Wamsley C, Hoopman J, Kenkel J. Use of Optical Coherence Tomography (OCT) in Aesthetic Skin Assessment—A Short Review. Lasers in Surgery and Medicine, Jan 2020

5. Jiang W-C, Zhang H, Xu Y, et al. Cutaneous vessel features of sensitive skin and its underlying functions. Skin Res Technol. 2019;00:1–7. https://doi. org/10.1111/srt.12819