High-resolution imaging with a multi-beam OCT device can accurately predict tumor margins of a BCC prior to Mohs micrographic surgery. This case was particularly interesting as the margin that was mapped represented a very ill-defined area where tumor extended into almost normal appearing skin. The OCT device was able to effectively depict the tumor extension. While this report evaluated only one margin of one tumor, the potential applications of the technology are obvious. With any tumor, particularly ill-defined ones, the use of OCT could potentially reduce the number of stages required to clear the tumor leading to shorter operative times and reduction of cost.